8-Br-cAMP誘導細胞分化
Catalog#: 1837-25 | Size: 25 mg
8-溴-環腺苷酸(8-bromo-cyclic 3，5 -adenosine monophosphat，8-Br-cAMP)可選擇性結合cAMP受體位點，誘導細胞分化
Description: A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. Also recently shown to improve the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells 2-fold.
Alternate Name/Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8-bromoadenosine- 3', 5'- monophosphate
Appearance: White to off-white solid
CAS Number: 76939-46-3
Molecular Formula: C₁₀H₁₀BrN₅O₆P. Na
Molecular Weight: 430.08
Purity: ≥98% by TLC
Solubility: H₂O (~100 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from moisture and light
USAGE: For Research Use Only! Not For Use in Humans
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