DNA修復基因沉默細胞株(Knockdown cell lines)，全新上市。
在BER路徑中，提供20種以上基因沉默細胞株。包括鹼基切除修復（BER）的途徑、錯配修復（MMR），和非同源末端連接（NHEJ）。特定shRNA慢病毒轉導之LN428膠質母細胞瘤，經由RT-PCR其基因沉默效能為63%~98%。其無特定病毒之污染，品質保證。
Tools to Study Genomic Instability and Genotoxic Stress
DNA Repair Gene Knockdown Cell Lines*
DNA repair proteins maintain the stability of the genome. When repair protein function is impaired through mutations, the genome may become unstable which is a hallmark of solid tumors. The availability of this panel of knockdown cell lines will permit scientists to study the molecular etiology of tumor genomic instability and to exploit it in oncology research. The Knockdown line encompasses the Base Excision Repair pathway, Non Homologous End Joining, and Mismatch Repair pathways. Trevigen’s Knockdown Cell Lines are target specific LN428 (glioblastoma) shRNA lentivirus transduced cells. They are rigorously qualified and mycoplasma free. The percent knockdown levels range from 63-98% as evaluated by RT-PCR. Lentiviruses are maintained by puromycin selection.
FEATURES:
- Tested negative for Mycoplasma
- Tested negative for: Human immunodeficiency virus (HIV1, HIV2), Hepatitis viruses (A, B,and C), Human T-lymphotropic virus (HTLV 1, HTLV 2), Epstein Barr, Hantaviruses Hantaan (Seoul, Sin, Nombre), Herpes simplex (1+2,) Human cytomegalovirus, Human herpes virus (6+8), Human adenovirus, Varicella virus and Lymphocytic Choriomeningitis virus.
ORDERING INFORMATION:
- *Cell lines are provided under an MTA.
Mismatch Repair | ||||
| Catalog # | Product Name | # of Cells Per Vial | Size | %KD by RT-PCR |
| 55027-001-01 | PMS2 Knock Down Cell Line (MTA Required prior to shipment) | 1x106 | 1 vial | 84% |
| 55028-001-01 | MLH3 Knock Down Cell Line (MTA required before shipment) | 1x106 | 1 vial | 71% |
| 55021-001-01 | MSH3 Knock Down Cell Line (MTA required before shipment) | 1x106 | 1 vial | 83% |
| 55034-001-01 | XRCC6 (Ku70) Knock Down Cell Line (MTA required before shipment) | 1x106 | 1 vial | 92% |
| 55026-001-01 | MLH1 Knock Down Cell Lines (MTA required to shipment) | 1x106 | 1 vial | 80% |
| 55024-001-01 | MSH5 Knock Down Cell Line (MTA required to shipment) | 1x106 | 1 vial | 92% |
| 55035-001-01 | XRCC5 (Ku80) Knock Down Cell Line (MTA required before shipment) | 1x106 | 1 vial | 85% |
| 55022-001-01 | MSH6 Knock Down Cell Line (MTA required to shipment) | 1x106 | 1 vial | 93% |
Non-Homologous End Joining | ||||
| Catalog # | Product Name | # of Cells Per Vial | Size | %KD by RT-PCR |
| 55037-001-01 | SIRTI Knock Down Cell Line (MTA required prior to shipment) | 1x106 | 1 vial | 95% |
| 55036-001-01 | PRKDC Knock Down Cell Line (MTA required prior to shipping) | 1x106 | 1 vial | 94% |
| 55038-001-01 | SIRTI2 Knock Down Cell Line (MTA required prior to shipping) | 1x106 | 1 vial | 98% |
Knockdown Control | ||||
| Catalog # | Product Name | # of Cells Per Vial | Size | %KD by RT-PCR |
| 5503-001-01 | Knock Down Control Cell Line (MTA Required prior to shipment) | 1x106 | 1 vial | N/A |
【供應廠商】萊恩生物科技有限公司
【公司電話】04-2523-9639
【業務專員】陳俊豪 0937-229803
【電子信箱】biolion0819@gmail.com
沒有留言:
張貼留言